In most hospitals worldwide specific rules have been implemented regarding the various phases of the hospitalization of patients – also regarding their treatment. these rules could be regarded as prevention measures – at least up to a level against the spread of infections in hospitals. However, because the specific issue is of significant importance, a series of relevant tests have been made in order to ensure the effectiveness of measures already established worldwide for the protection from infections developed in hospitals. additional control measures have been also proposed taking into account the characteristics of each one infection but also the funds available for the realization of relevant projects.The current paper focuses on the identification and the proposal of the most effective measures towards the limitation of the risk of infection by Methicillin-Resistant Staphylococcus Aureus in hospital patients. It should be also noticed that in literature and the empirical research, the need for appropriate measures regarding the limitation of infections in hospitals is highlighted. however, the proposals made could be characterized as offering a rather partial resolution to the particular problem. For this reason, the critical analysis of the findings of these studies has been considered to be helpful for the identification of the most appropriate measures for the limitation of the specific disease in hospital patients.The limitation of the development of Methicillin-Resistant staphylococcus in hospitals has been an issue extensively examined by medical researchers internationally. A series of infection control measures have been proposed against the spread of this disease. the effectiveness of these measures has been doubted taking into account the findings of relevant clinical studies.